波谱学杂志

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基于自监督扩散先验和同时多层激发成像的磁共振图像网络重建

王浩博1,2,刘聪聪3,吴星阳2,周硕2,方福衣4,杨兴5,崔卓须2,王海峰1,2*   

  1. 1. 中国科学院大学,北京 100049;2. 劳特伯生物医学成像研究中心,中国科学院深圳先进技术研究院,广东 深圳 518055;3. 医学人工智能研究中心,中国科学院深圳先进技术研究院,广东 深圳 518055;4. 上海联影医疗科技股份有限公司,上海 201807;5. 国家高性能医疗器械创新中心,广东 深圳 518055
  • 收稿日期:2026-07-27 修回日期:2026-08-25 接受日期:2026-09-15
  • 通讯作者: 王海峰 E-mail:hf.wang1@siat.ac.cn
  • 基金资助:
    了国家重点研发计划(2023YFB3811400); 国家自然科学基金(62271474); 中国科学院全球共性挑战专项(321GJHZ2023246GC); 中国科学院超导研究专项(SCZX-0301); 广东省基础与应用基础研究基金(2023B1515120007); 广东省基础与应用基础研究基金(2024A1515012138); 深圳市科技计划项目(KJZD20230923113259001)

Self-Supervised Diffusion Prior–Based Network for Simultaneous Multi-Slice MRI Reconstruction

WANG Haobo1,2,LIU Congcong3,WU Xingyang2,ZHOU Shuo2,FANG Fuyi4,YANG Xing5, CUI Zhuoxu2,WANG Haifeng1,2*   

  1. 1. University of Chinese Academy of Sciences, Beijing 100049, China; 2. Paul C. Lauterbur Research Center for Biomedical Imaging, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China; 3. Research Center for Medical AI, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China; 4. Shanghai United Imaging Healthcare Co., Ltd., Shanghai 201807, China; 5. National Innovation Center for Advanced Medical Devices, Shenzhen 518055, China
  • Received:2026-07-27 Revised:2026-08-25 Accepted:2026-09-15
  • Contact: WANG Haifeng E-mail:hf.wang1@siat.ac.cn

摘要: 同时多层(SMS)成像与面内欠采样叠加时,重建需从高度折叠且欠采样的K空间中同时完成解折叠与去混叠.针对现有扩散模型重建中数据一致性以固定强度施加、且预训练先验难以自适应当次扫描的问题,提出一种结合几何门控数据一致性与测试时低秩自适应的SMS重建方法.该方法在每一反向采样步中,将数据一致性修正量相对去噪器局部切空间分解为切向与法向分量,切向分量完整保留、法向分量经自适应门控注入,以抑制离流形伪影;并在得分网络中并联低秩旁支,冻结主干权重,仅以测量一致性损失在推理阶段做少步微调.基于fastMRI脑部T2加权数据的仿真实验表明,该方法在全部条件下均优于5种对比方法,峰值信噪比相对于次优方法提升2.27~5.45 dB,且随加速倍数增大的性能退化更为平缓.

关键词: 磁共振成像, 多层同时成像, 扩散模型, 深度学习, 测试时自适应

Abstract:

When simultaneous multi-slice (SMS) imaging is combined with in-plane undersampling, reconstruction must unfold superimposed slices and remove aliasing simultaneously from a highly folded, undersampled K-space. To address the fixed-strength data consistency and the prior-scan mismatch in existing diffusion-based reconstructions, an SMS reconstruction method combining geometry-gated data consistency with test-time low-rank adaptation is proposed. At each reverse sampling step, the data-consistency correction is decomposed with respect to the local tangent space of the denoiser: the tangential component is retained in full, whereas the normal component is admitted through an adaptive gate, suppressing off-manifold artefacts. Low-rank branches are further attached to the score network and updated at inference using a measurement-consistency loss alone, with the backbone frozen. Experiments on simulated fastMRI brain T2-weighted data show that the proposed method outperforms five comparison methods under all conditions, with PSNR gains of 2.27~5.45 dB over the second-best method and a more graceful degradation as acceleration increases.

Key words: Magnetic resonance imaging, Simultaneous multi-slice imaging, Diffusion model, Deep learning, Test-time adaptation