我国高场及超高场磁共振成像设备研制和市场化的机遇与挑战

doi:10.11938/cjmr20243142

波谱学杂志 ›› 2025, Vol. 42 ›› Issue (3): 334-344.doi: 10.11938/cjmr20243142cstr: 32225.14.cjmr20243142

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我国高场及超高场磁共振成像设备研制和市场化的机遇与挑战

马滢雪¹^,², 赵晏强¹^,², 杨晓冬³, 蒋滨⁴, 陶诚¹^,²^,^*()

1.中国科学院武汉文献情报中心，科技大数据湖北省重点实验室，湖北武汉 430071
2.中国科学院大学经济与管理学院信息资源管理系，湖北武汉 430071
3.中国科学院苏州生物医学工程技术研究所，江苏苏州 215163
4.中国科学院精密测量科学与技术创新研究院，湖北武汉 430071

收稿日期:2024-12-30 出版日期:2025-09-05 在线发表日期:2025-02-10
通讯作者: * Tel: 027-87197630, E-mail: taoch@mail.whlib.ac.cn.
基金资助:
中国科学院科研装备研制项目(YJKYYQ20210051);中国科学院研究所科研创新能力评估与服务示范(E2KZ111001)

Opportunities and Challenges of High-field and Ultra-high-field Magnetic Resonance Imaging in China

MA Yingxue¹^,², ZHAO Yanqiang¹^,², YANG Xiaodong³, JIANG Bin⁴, TAO Cheng¹^,²^,^*()

1. Hubei Key Laboratory of Big Data in Science and Technology, National Science Library (Wuhan), Chinese Academy of Sciences, Wuhan, 430071, China
2. Department of Information Resources Management, School of Economics and Management, University of Chinese Academy of Sciences, Wuhan, 430071, China
3. Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou, 215163, China
4. Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences, Wuhan, 430071, China

Received:2024-12-30 Published:2025-09-05 Online:2025-02-10
Contact: * Tel: 027-87197630, E-mail: taoch@mail.whlib.ac.cn.

摘要/Abstract

摘要：

磁共振成像（MRI）作为一种无创的高分辨医学影像技术，是临床医学诊断的利器，当前MRI不断向更高磁场强度发展．高场及超高场MRI在临床医学诊断及新兴前沿成像技术等领域上展现出明显优势，成为全球各国竞相突破的方向．高场及超高场MRI设备是科学研究和临床应用的重要保障，各国均将其作为重要战略行业予以重视和支持．本文全面分析了高场及超高场MRI设备的国内外市场格局、核心技术竞争态势，重点讨论了我国发展面临的机遇与挑战，并提出了针对性建议．

关键词: 磁共振成像（MRI）, 超高场, 人工智能, 磁体

Abstract:

Magnetic resonance imaging (MRI), as a non-invasive, high-resolution medical imaging technology, is a powerful tool for clinical disease diagnosis. Current MRI systems are advancing towards higher magnetic field strength. High-field (HF) and ultra-high-field (UHF) MRI have demonstrated substantial advantages in clinical diagnosis and emerging cutting-edge imaging technologies, making them a focus of global competition. HF and UHF MRI equipment serves as a fundamental guarantee for scientific research and clinical applications, and is emphasized and supported as a strategic industry in many countries. This paper comprehensively analyzes the global market landscape and core technology competition in HF and UHF MRI equipment, highlights opportunities and challenges for China’s development in this field, and proposes targeted recommendations.

Key words: magnetic resonance imaging (MRI), ultra-high-field, AI, magnets

中图分类号:

O482.53

马滢雪, 赵晏强, 杨晓冬, 蒋滨, 陶诚. 我国高场及超高场磁共振成像设备研制和市场化的机遇与挑战[J]. 波谱学杂志, 2025, 42(3): 334-344.

MA Yingxue, ZHAO Yanqiang, YANG Xiaodong, JIANG Bin, TAO Cheng. Opportunities and Challenges of High-field and Ultra-high-field Magnetic Resonance Imaging in China[J]. Chinese Journal of Magnetic Resonance, 2025, 42(3): 334-344.

图/表 5

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参考文献 53

[1]	LADD M E, BACHERTT P, et al. Pros and cons of ultra-high-field MRI/MRS for human application[J]. Prog Nucl Magn Reson Spectrosc 2018, 109: 1-50.
[2]	SEO J H, CHUNG J Y. A preliminary study for reference RF coil at 11.7 T MRI: Based on electromagnetic field simulation of hybrid-BC RF coil according to diameter and length at 3.0, 7.0 and 11.7 T[J]. Sensors, 2022, 22(4): 1512.
[3]	BRUSCHI N, BOFFA G, INGLESE M. Ultra-high-field 7-T MRI in multiple sclerosis and other demyelinating diseases: from pathology to clinical practice[J]. Eur Radiol Exp, 2020, 4(1): 59. doi: 10.1186/s41747-020-00186-x pmid: 33089380
[4]	GAO J H, LEI H, CHEN Q, et al. Magnetic resonance imaging: progresses and perspectiv[J]. Science China-Life Sciences, 2020, 50(11): 1285-1295.
	高家红, 雷皓, 陈群, 等. 磁共振成像发展综述[J]. 中国科学: 生命科学, 2020, 50(11): 1285-1295.
[5]	ZHENG H R, WU Y, HE Q, et al. Fast and high-resolution magnetic resonance imaging on high field system[J]. Life Science Instruments, 2018, 16: 29-54.
	郑海荣, 吴垠, 贺强, 等. 基于高场磁共振的快速高分辨成像[J]. 生命科学仪器, 2018, 16: 29-54.
[6]	BUDINGER T F, BIRD M D. MRI and MRS of the human brain at magnetic fields of 14 T to 20 T: Technical feasibility, safety, and neuroscience horizons[J]. NeuroImage, 2018, 168: 509-531.
[7]	ZARETSKAYA N, FISCHL B, REUTER M, et al. Advantages of cortical surface reconstruction using submillimeter 7 T MEMPRAGE[J]. NeuroImage, 2018, 165: 11-26.
[8]	VACHHA B, HUANG S Y. MRI with ultrahigh field strength and high-performance gradients: challenges and opportunities for clinical neuroimaging at 7 T and beyond[J]. Eur Radiol Exp, 2021, 5(1): 35. doi: 10.1186/s41747-021-00216-2 pmid: 34435246
[9]	MORRISON M A, LUPO J M. 7-T magnetic resonance imaging in the management of brain tumors[J]. Magn Reson Imaging Clin N Am, 2021, 29(1): 83-102. doi: 10.1016/j.mric.2020.09.007 pmid: 33237018
[10]	VERMA G, DELMAN B N, BALCHANDANI P. Ultrahigh field MR imaging in epilepsy[J]. Magn Reson Imaging Clin N Am, 2021, 29(1): 41-52. doi: 10.1016/j.mric.2020.09.006 pmid: 33237014
[11]	DUZEL E, COSTAGLI M, DONATELLI G, et al. Studying Alzheimer disease, Parkinson disease, and amyotrophic lateral sclerosis with 7-T magnetic resonance[J]. Eur Radiol Exp, 2021, 5(1): 36-53. doi: 10.1186/s41747-021-00221-5 pmid: 34435242
[12]	DONATELLI G, CERAVOLO R, FROSINI D, et al. Present and future of ultra-high field MRI in neurodegenerative disorders[J]. Curr Neurol Neurosci, 2018, 18(6): 31-46. doi: 10.1007/s11910-018-0841-7 pmid: 29679161
[13]	GE J Q, GAO J H. A review of functional MRI application for brain research of Chinese language processing[J]. Magn Reson Lett, 2023, 3(1): 1-13.
[14]	LEE S P, SILVA A C, UGURBIL K, et al. Diffusion-weighted spin-echo fMRI at 9.4 T: Microvascular/tissue contribution to BOLD signal changes[J]. Magn Reson Med, 1999, 42(5): 919-928. pmid: 10542351
[15]	LEWIS L D, SETSOMPOP K, ROSEN B R, et al. Stimulus-dependent hemodynamic response timing across the human subcortical-cortical visual pathway identified through high spatiotemporal resolution 7T fMRI[J]. NeuroImage, 2018, 181: 279-291. doi: S1053-8119(18)30563-9 pmid: 29935223
[16]	TIAN Y T, LI C M, CHEN M. Research progress of chemical exchange saturation transfer magnetic resonance imaging in neurodegenerative disease[J]. Chinese J Magn Reson Imaging, 2023, 14(1): 32-47.
	田瑶天, 李春媚, 陈敏. 化学交换饱和转移成像在神经退行性疾病中的研究进展[J]. 磁共振成像, 2023, 14(1): 32-47.
[17]	LIEBERT A, TKOTZ K, HERRLER J, et al. Whole-brain quantitative CEST MRI at 7T using parallel transmission methods and $\text{B}_{\text{1}}^{\text{+}}$ correction[J]. Magn Reson Med, 2021, 86(1): 346-362.
[18]	MEISSNER J E, KORZOWSKI A, REGNERY S, et al. Early response assessment of glioma patients to definitive chemoradiotherapy using chemical exchange saturation transfer imaging at 7 T[J]. J Magn Reson Imaging, 2019, 50(4): 1268-1277.
[19]	PAECH D, WINDSCHUH J, OBERHOLLENZER J, et al. Assessing the predictability of IDH mutation and MGMT methylation status in glioma patients using relaxation-compensated multipool CEST MRI at 7.0 T[J]. Neuro-Oncology, 2018, 20(12): 1661-1671.
[20]	WANG G X, YANG H Y, LI J, et al. Overview and progress of X-nuclei magnetic resonance imaging in biomedical studies[J]. Magn Reson Lett, 2023, 3(4): 327-343.
[21]	ZHANG H, CHENG G X, CHEN Y J, et al. Ultra-high field magnetic resonance imaging technology and clinical application[J]. Chinese Journal of CT and MRI, 2020, 18(8): 168-173.
	张宏, 成官迅, 陈延军, 等. 超高场磁共振成像技术与临床应用[J]. 中国CT和MRI杂志, 2020, 18(8): 168-173.
[22]	KRAFF O, FISCHER A, NAGEL A M, et al. MRI at 7 Tesla and above: demonstrated and potential capabilities[J]. J Magn Reson Imaging, 2015, 41(1): 13-33. doi: 10.1002/jmri.24573 pmid: 24478137
[23]	中商产业研究院. 2022年中国MRI行业市场规模及竞争格局预测分析[EB/OL]. [2022-11-01]. https://www.askci.com/news/chanye/20221101/1708442005688.shtml
[24]	Business Wire. Global magnetic resonance imaging market report2023[EB/OL]. [2023-07-18]. https://www.businesswire.com/news/home/20230718139200/en/Global-Magnetic-Resonance-Imaging-Market-Report-2023-Increase-in-Healthcare-Spending-Drives-Growth
[25]	TRATTNIG S, HANGEL G, ROBINSON S D, et al. Ultrahigh-field MRI: where it really makes a difference[J]. Radiologie, 2023, 64(s1): 1-8.
[26]	健康界. 中国有多少台7 T磁共振[EB/OL]. [2023-09-05]. https://www.cn-healthcare.com/articlewm/20230902/content-1600638.html
[27]	器械之家. 刚刚, 西门子7 T磁共振获NMPA批准[EB/OL]. [2022-06-10]. http://www.qixieke.com/Font/index/detailPage.html?id=773-115
[28]	YANG W H. The development of ultra-high field magnetic resonance imaging[J]. Physics, 2019, 48 (4): 227-236.
	杨文晖. 磁共振成像发展与超高场磁共振成像技术[J]. 物理, 2019, 48 (4): 227-236.
[29]	LIU L H, JIANG B, CHEN D X, et al. The Status and challenge of the domestic manufacturing of superconduct magnetic resonance instruments in China[J]. Chinese J Magn Reson, 2022, 39(3): 345-355.
	刘莲花, 蒋滨, 陈代谢, 等. 超导磁共振仪器设备国产化现状及挑战[J]. 波谱学杂志, 2022, 39(3): 345-355. doi: 10.11938/cjmr20212961
[30]	未来智库. 2023年辰光医疗研究报告: 国内唯二MRI超导磁体独立供应商, 新拓光伏市场[EB/OL]. [2023-07-13]. https://www.vzkoo.com/read/202307136a5b3949632e11ce1bb7e03d.html
[31]	新浪财经网. 2022年中国磁共振行业成绩公布[EB/OL]. [2023-03-08]. https://finance.sina.com.cn/stock/med/zbsc/2023-03-28/doc-imynktuf8267041.shtml
[32]	日商环球讯息有限公司. 全球超导磁体市场[EB/OL]. [2023-08.04]. https://cn.gii.tw/report/go1321211-superconducting-magnets.html
[33]	Healthcare-in-Europe.com. 11.7 Tesla: First images from the world's most powerful MRI scanner[EB/OL]. [2024-03]. https://healthcare-in-europe.com/en/news/11-7-tesla-first-images-world-most-powerful-mri-scanner.html
[34]	特斯拉(Tesla)官网. 核磁共振磁体介绍[EB/OL]. http://www.tesla.co.uk/chinese/magnet/tesla-engineering-magnet-division-suprconducting-magnets/tesla-engineering-magnet-division-mri-magnets.html
[35]	美通社. ASG和西门子医疗联手交付超高场MRI系统[EB/OL]. [2023-01-18]. https://www.prnasia.com/story/390913-1.shtml
[36]	中国科学报. 9.4T超高场人体磁共振成像超导磁体研制成功[EB/OL]. [2022-05-18]. https://www.cas.cn/cm/202205/t20220518_4834943.shtml
[37]	QYResearch. 2024-2030全球与中国磁共振梯度线圈市场现状及未来发展趋势[EB/OL]. [2024-04-25]. https://www.qyresearch.com.cn/reports/3876734/magnetic-resonance-imaging-gradient-coil
[38]	Dataintelo. MRI gradient coil market[EB/OL]. https://dataintelo.com/report/mri-gradient-coil-market
[39]	新思界网. [聚焦]梯度系统是磁共振(MRI)设备重要组成我国整机企业以外部采购为主[EB/OL]. [2024-12-02]. https://mp.ofweek.com/medical/a556714690597
[40]	普华有策. 2021-2026年磁共振射频线圈行业趋势及投资可行性分析报告报告[EB/OL]. https://www.phpolicy.com/chanpinyufuwu/491468.html
[41]	WISE GUY reports. 全球MRI射频线圈市场研究报告[EB/OL]. [2024-09-04]. https://www.wiseguyreports.com/cn/reports/mri-rf-coil-market
[42]	电子工程专辑(EET). 比最快超算快一亿亿倍!“九章三号”光量子计算原型机再度刷新记录[EB/OL]. [2023-10-11]. https://www.eet-china.com/news/202310115445.html
[43]	The Next Web(TNW). Microsoft wants to revolutionize MRIs with quantum-inspired algorithms and HoloLens[EB/OL]. [2018-05-19]. https://thenextweb.com/news/microsoft-wants-to-use-quantum-inspired-algorithms-and-hololens-to-revolutionize-mris
[44]	费米国家加速器实验室(Fermilab)官网. NYU Langone plans to partner with Fermilab’s SQMS to advance MRI analysis[EB/OL]. [2022-07-20]. https://news.fnal.gov/2022/07/nyu-langone-plans-to-partner-with-fermilabs-sqms-to-advance-mri-analysis/
[45]	WANG M Y. Research status and development prospect of magnetic resonance imaging artificial intelligence[J]. Chinese J Magn Reson Imaging, 2023, 14(3): 1-5.
	王梅云. 磁共振成像人工智能的研究现状及发展前景[J]. 磁共振成像, 2023, 14(3): 1-5.
[46]	中国经济网. AI在医学影像领域应用提速[EB/OL]. [2023-05-19]. http://www.ce.cn/cysc/yy/hydt/202305/19/t20230519_38552560.shtml.
[47]	中国信通院&36氪研究院. 《2020人工智能医疗产业发展蓝皮书》[EB/OL]. [2020-09-08]. http://www.caict.ac.cn/kxyj/qwfb/ztbg/202009/P020200910495521359097.pdf
[48]	中国报告大厅. 2024年人工智能医疗行业分析[EB/OL]. https://www.chinabgao.com/freereport/97253.html
[49]	36氪研究院. 《2021年中国医疗AI行业研究报告》[EB/OL]. [2021-12-21]. https://13115299.s21i.faiusr.com/61/1/ABUIABA9GAAg_Ze1jgYogbjD1gE.pdf
[50]	华经情报网. 2023年全球及中国MRI行业现状分析, 人均保有量有望进一步提升[EB/OL]. [2023-08-16]. https://www.huaon.com/channel/trend/918943.html
[51]	奥泰医疗官网. 奥泰•历程2005-2020[OL]. http://alltechmed.com/corporate/history
[52]	证券时报网. 跻身全球一流水平国产磁共振仪器再上新台阶[EB/OL]. [2023-09-12]. https://stock.stockstar.com/IG2023091200009408.shtml
[53]	MA Y X, HAO Q L, ZHAO Y Q. Analysis of the development status of global high-end magnetic resonance imaging based on patents[J]. China Medical Devices, 2024, 39(4): 109-115.
	马滢雪, 蒿巧利, 赵晏强. 基于专利的全球高端磁共振成像发展现状分析[J]. 中国医疗设备, 2024, 39(4): 109-115.

主要MRI企业	国家	MRI设备主要场强
通用电气福纳公司	美国	1.5 T、3.0 T、7.0 T 1.5 T、3.0 T
飞利浦	荷兰	1.5 T、3.0 T
西门子	德国	1.5 T、3.0 T、7.0 T
佳能医疗日立公司富士胶片公司	日本	1.5 T、3.0 T 1.5 T、3.0 T 1.5 T、3.0 T
联影医疗东软医疗	中国	1.5 T、3.0 T、5.0 T 1.5 T、准3.0 T

磁共振核心部件	国外主要机构	国内主要机构	目前形势
磁体	美国GE、德国西门子和布鲁克、荷兰飞利浦、日本三菱、英国特斯拉公司、意大利ASG超导体公司	宁波健信、辰光医疗、联影医疗、东软医疗、奥泰医疗、中国科学院电工研究所	国内外差距较大，中高端产品以进口为主
梯度系统	美国GE、德国西门子和布鲁克、荷兰飞利浦、澳大利亚磁力公司	联影医疗、宁波健信、东软医疗	国内外差距较大，以进口为主
射频系统	美国Invivo、GE和美国仪器公司、荷兰飞利浦、英国特斯拉公司和MR线圈科技公司、德国西门子和布鲁克公司、日本东芝	联影医疗、辰光医疗	国内外差距较大，以进口为主
计算机系统（量子计算机研发）	美国麻省理工大学、德国斯图加特大学、荷兰代尔夫特理工大学	中国科学技术大学、清华大学、南方科技大学	研发阶段，我国比肩美国，处于世界一流水平

我国高场及超高场磁共振成像设备研制和市场化的机遇与挑战

Opportunities and Challenges of High-field and Ultra-high-field Magnetic Resonance Imaging in China

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