波谱学杂志

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一种用于低场磁共振波谱仪的圆极化线圈设计

汤世豪1,2,杨谨毓1,2,徐雅洁2#,王亚2,彭博文1,2,高宇昊1,2,杨晓冬2*   

  1. 1. 中国科学技术大学生物医学工程学院(苏州),生命科学与医学部,江苏 苏州 215163;2. 中国科学院苏州生物医学工程技术研究所,江苏 苏州 215163
  • 收稿日期:2025-03-17 修回日期:2025-04-05 出版日期:2025-04-23 在线发表日期:2025-04-23
  • 通讯作者: 徐雅洁;杨晓冬 E-mail:xuyj@sibet.ac.cn;xiaodong.yang@sibet.ac.cn

A Design of Circularly Polarized Coil for Low-Field Nuclear Magnetic Resonance Spectrometers

TANG Shihao1,2,YANG Jinyu1,2,XU Yajie2#,WANG Ya2,PENG Bowen1,2,GAO Yuhao1,2,YANG Xiaodong2*   

  1. 1. School of Biomedical Engineering (Suzhou), Division of Life Sciences and Medicine, University of Science and Technology of China, Suzhou 215163, China; 2. Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou 215163, China
  • Received:2025-03-17 Revised:2025-04-05 Published:2025-04-23 Online:2025-04-23
  • Contact: XU Yajie;YANG Xiaodong E-mail:xuyj@sibet.ac.cn;xiaodong.yang@sibet.ac.cn

摘要: 信噪比(SNR)是影响桌面磁共振波谱仪信号质量的一个关键参数,在探头中使用正交圆极化线圈是提升信噪比的有效手段,由于桌面磁共振波谱仪磁体结构紧凑,留给探头空间有限,对圆极化线圈的设计造成挑战.在桌面磁共振波谱仪中未有其它研究者采用过圆极化线圈.基于实验室自研桌面磁共振波谱仪平台,本文设计并制作了一套基于柔性版的收发一体圆极化线圈,该线圈由一组正交的鞍形线圈和亥姆霍兹线圈构成.首先根据探测目标区域的结构参数确定了单匝线圈的支撑结构与尺寸,然后使用Ansys Maxwell磁场仿真软件确定了圆极化线圈的最优匝数,最后使用自研圆极化探头结合外围射频电路对CuSO4溶液进行了测试并以此评估该圆极化线圈的性能.实验结果表明,组合构成的圆极化线圈与单通道鞍形线圈和亥姆霍兹线圈相比,SNR分别提升了28.78%和29.21%,发射功率约节省了37.5%,证明圆极化线圈能够有效提升桌面磁共振波谱仪探头性能.

关键词: 磁共振波谱(MRS), 正交线圈, 线圈优化, 双通道探头

Abstract: Signal-to-noise ratio (SNR) is a key parameter governing signal quality in benchtop MRS spectrometers, where quadrature circularly polarized coils offer an effective means to enhance SNR. However, the confined space within the compact magnets of desktop systems poses challenges for implementing such coils—a strategy previously unattempted in this domain. Leveraging a self-developed desktop MRS platform, this study designed and fabricated a flexible printed circuit-based transceiver-integrated circularly polarized coil system, comprising orthogonally arranged saddle and Helmholtz coils. The coil geometry was optimized through Ansys Maxwell simulations, and experimental validation using CuSO₄ solution demonstrated SNR improvements of 28.78% and 29.21% over single-channel saddle and Helmholtz coils, respectively, alongside a 37.5% reduction in reflected power. These results confirm the viability of circularly polarized coils for advancing desktop MRS probe performance.

Key words: Nuclear Magnetic Resonance (NMR), Circularly Polarized Coils, Coil Optimization, dual-channel probe