研究简报

卢立康唑的波谱学特征和结构确证

  • 林云良 ,
  • 高红梅 ,
  • 李锋 ,
  • 陈相峰
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  • 齐鲁工业大学(山东省科学院), 山东省分析测试中心, 山东 济南 250014

收稿日期: 2018-03-14

  网络出版日期: 2018-08-28

基金资助

国家自然科学基金青年科学基金项目(21506119).

Spectral Analysis and Structural Elucidation of Luliconazole

  • LIN Yun-liang ,
  • GAO Hong-mei ,
  • LI Feng ,
  • CHEN Xiang-feng
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  • Shandong Analysis and Test Center, Qilu University of Technology(Shandong Academy of Sciences), Ji'nan 250014, China

Received date: 2018-03-14

  Online published: 2018-08-28

摘要

用红外吸收光谱、紫外吸收光谱、核磁共振(NMR)波谱(包含1H NMR、13C NMR、DEPT135、1H-1H COSY、1H-13C HMQC和1H-13C HMBC)、质谱、差示扫描量热分析、X-射线粉末衍射和元素分析等方法对卢立康唑进行了结构分析.对卢立康唑所有的1H和13C NMR信号进行了归属,并通过多种谱学技术确证了卢立康唑的结构.

本文引用格式

林云良 , 高红梅 , 李锋 , 陈相峰 . 卢立康唑的波谱学特征和结构确证[J]. 波谱学杂志, 2018 , 35(3) : 385 -392 . DOI: 10.11938/cjmr20182620

Abstract

Infrared spectra, ultraviolet spectra, nuclear magnetic resonance (NMR) spectra (i.e., 1H NMR, 13C NMR, DEPT135, 1H-1H COSY, 1H-13C HMQC and 1H-13C HMBC) and mass spectra of luliconazole were collected and used to characterize the compound. Differential scanning calorimetry, X-ray power diffraction and elementary analysis were also performed. All 1H and 13C NMR signals of the compound were assigned. The structure of the compound was determined.

参考文献

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