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高场磁共振成像1H/31P双调谐射频线圈研究进展

  • 马聪伟 ,
  • 杨鸿毅 ,
  • 钟凯
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  • 1. 中国科学院 强磁场科学中心, 安徽 合肥 230031;
    2. 中国科学技术大学, 安徽 合肥 230026

收稿日期: 2020-04-13

  网络出版日期: 2020-06-08

基金资助

国家重点研发计划(2018YFE0205700);中科院合肥大科学中心“高端用户培育基金”资助项目(2019HSC-UE006).

Research Progresses of High-Field MRI 1H/31P Dual-Tuned Radio Frequency Coil

  • MA Cong-wei ,
  • YANG Hong-yi ,
  • ZHONG Kai
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  • 1. High Magnetic Field Laboratory, Chinese Academy of Sciences, Hefei 230031, China;
    2. University of Science and Technology of China, Hefei 230026, China

Received date: 2020-04-13

  Online published: 2020-06-08

摘要

在众多可产生磁共振现象的原子核中,1H核凭借其在生物体中含量高、磁共振信号强的优势,成为磁共振成像的主要研究对象.但其它杂核在生命科学相关研究中同样具有不可替代的独特性,如31P核广泛参与了生物体内的能量代谢过程,是非质子成像研究领域的重要内容.MRI向更高场强的发展使得杂核成像逐渐普及,其核心部件是高质量的1H/31P双调谐射频线圈.本文总结了与1H/31P双调谐射频线圈相关的研究与应用,展示了9.4 T下小鼠脑的质子磁共振成像及磁共振磷谱,并讨论了高场1H/31P双调谐射频线圈的潜在应用价值.

本文引用格式

马聪伟 , 杨鸿毅 , 钟凯 . 高场磁共振成像1H/31P双调谐射频线圈研究进展[J]. 波谱学杂志, 2021 , 38(1) : 118 -139 . DOI: 10.11938/cjmr20202826

Abstract

1H nucleus is the most commonly used nucleus for magnetic resonance imaging (MRI) due to its high natural abundance in organisms and high MR sensitivity. However, other nuclei are distinctive in physiological processes, such as 31P that is important in the energy metabolisms. The development of high-field MRI allows for MRI research based on 31P nucleus, while high-quality 1H/31P dual-tuned radio frequency (RF) coil is essential for such applications. This article summarized the researches and applications of various 1H/31P dual-tuned RF coils, and presented in vivo 1H MRI and 31P MR spectra of mouse brain at 9.4 T. Potential applications of 1H/31P dual-tuned RF coil for high field were discussed.

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