研究简报

苦皮藤中两个新的 β-二氢沉香呋喃型化合物的 NMR 数据解析

  • 廖怀玉 ,
  • 韩红园 ,
  • 陈飞 ,
  • 张海艳 ,
  • 杨静 ,
  • 赵天增
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  • 1. 河南中医药大学, 河南 郑州 450046;
    2. 河南省科学院 天然产物重点实验室, 河南 郑州 450002

收稿日期: 2020-09-28

  网络出版日期: 2020-11-16

基金资助

“重大新药创制”科技重大专项(2018ZX09711001-008-004).

An NMR Study on Two New β-Dihydroagrofuran Compounds in Celastrus angulatus Maxim

  • LIAO Huai-yu ,
  • HAN Hong-yuan ,
  • CHEN Fei ,
  • ZHANG Hai-yan ,
  • YANG Jing ,
  • ZHAO Tian-zeng
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  • 1. Henan University of Traditional Chinese Medicine, Zhengzhou 450046, China;
    2. Key Laboratory of Natural Products, Henan Academy of Science, Zhengzhou 450002, China

Received date: 2020-09-28

  Online published: 2020-11-16

摘要

从南蛇藤属植物苦皮藤中分离出两个新的β-二氢沉香呋喃型化合物:1β,2β,15-三乙酰氧基-8α-(α-甲基)-丁酰氧基-9β-苯甲酰氧基-4α,6α-二羟基-β-二氢沉香呋喃(化合物I)和1β,15-二乙酰氧基-8α-(α-甲基)-丙酰氧基-2β,9β-二苯甲酰氧基-4α,6α-二羟基-β-二氢沉香呋喃(化合物II).通过核磁共振(NMR,包括1H NMR、13C NMR、DEPT、1H-1H COSY、NOESY、HSQC、HMBC)技术对化合物所有的1H和13C NMR信号进行了全归属和详细解析.

本文引用格式

廖怀玉 , 韩红园 , 陈飞 , 张海艳 , 杨静 , 赵天增 . 苦皮藤中两个新的 β-二氢沉香呋喃型化合物的 NMR 数据解析[J]. 波谱学杂志, 2021 , 38(1) : 101 -109 . DOI: 10.11938/cjmr20202862

Abstract

Two new β-dihydroagrofuran compounds, 1β,2β,15-triacetoxy-8α-(α-methyl)-butanoyloy-9β-benzoxy-4α,6α- dihydroxy-β-dihydroagrofuran (compound I) and 1β,15-diacetoxy-8α-(α-methyl)-propionyloxy-2β,9β-dibenzoxy-4α,6α- dihydroxy-β-dihydroagrofuran (compound II), were isolated from Celastrus angulatus Maxim. The chemical shifts of the two new compounds were assigned by one- and two-dimensional nuclear magnetic resonance (NMR) techniques. Their structures were elucidated.

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