超导磁共振仪器设备国产化现状及挑战
收稿日期: 2021-12-03
网络出版日期: 2021-12-28
基金资助
国家重点研发计划资助项目(2018YFA0704002);国家自然科学基金资助项目(21735007)
The Status and Challenge of the Domestic Manufacturing of Superconduct Magnetic Resonance Instruments in China
Received date: 2021-12-03
Online published: 2021-12-28
刘莲花 , 蒋滨 , 陈代谢 , 苏驰 . 超导磁共振仪器设备国产化现状及挑战[J]. 波谱学杂志, 2022 , 39(3) : 345 -355 . DOI: 10.11938/cjmr20212961
Magnetic resonance (MR) plays an essential role in chemical analysis and medical imaging. The reliable MR instrument is a prerequisite for MR related research. Foreign instrument companies have monopolized the MR instrument supply in China for a long time. Recently, the situation has witnessed impressive improvement due to progress made by Chinese domestic companies and institutions in developing and manufacturing MR instruments. This paper surveyed and reviewed the status and challenges of the domestic manufacturing of MR instruments in China.
Key words： magnetic resonance (MR); instrument; domestic manufacturing; status
| 1 | PAULI W . Zur frage der theoretischen deutung der satelliten einiger spektrallinien und ihrer beeinflussung durch magnetische Felder[J]. Naturwissenschaften, 1924, 12 (37): 741- 743. |
| 2 | KELLOG J M B , RABI I I , RAMSEY N F , et al. The magnetic moments of the proton and the deuteron - The radiofrequency spectrum of H-2 in various magnetic fields[J]. Phys Rev, 1939, 56 (8): 728- 743. |
| 3 | BLOCH F . Nuclear induction[J]. Phys Rev, 1946, 70 (7, 8): 460- 474. |
| 4 | PURCELL E M , TORREY H C , POUND R V . Resonance absorption by nuclear magnetic moments in a solid[J]. Phys Rev, 1946, 69 (1, 2): 37- 38. |
| 5 | PROCTOR W G , YU F C . The dependence of a nuclear magnetic resonance frequency upon chemical compound[J]. Phys Rev, 1950, 77 (5): 717. |
| 6 | ARNOLD J T , DHARMATTI S S , PACKARD M E . Chemical effects on nuclear induction signals from organic compounds[J]. J Chem Phys, 1951, 19 (4): 507. |
| 7 | GUTOWSKY H S , MCCALL D W . Nuclear magnetic resonance fine structure in liquids[J]. Phys Rev, 1951, 82 (5): 748- 749. |
| 8 | SHOOLERY J N , ROGERS M T . Nuclear magnetic resonance spectra of steroids[J]. J Am Chem Soc, 1958, 80 (19): 5121- 5135. |
| 9 | LAUTERBUR P C . C-13 nuclear magnetic resonance spectra[J]. J Chem Phys, 1957, 26 (1): 217- 218. |
| 10 | ERNST R R , ANDERSON W A . Application of Fourier transform spectroscopy to magnetic resonance[J]. Rev Sci Instrum, 1966, 37 (1): 93. |
| 11 | AUE W P , BARTHOLDI E , ERNST R R . Two-dimensional spectroscopy. Application to nuclear magnetic resonance[[J]. J Chem Phys, 1976, 64 (5): 2229- 2246. |
| 12 | SAUNDERS M , WISHNIA A , KIRKWOOD J G . The nuclear magnetic resonance spectrum of ribonuclease[J]. J Am Chem Soc, 1957, 79 (12): 3289- 3290. |
| 13 | WILLIAMSON M P , HAVEL T F , WüTHRICH K . Solution conformation of proteinase inhibitor ⅡA from bull seminal plasma by 1H nuclear magnetic resonance and distance geometry[J]. J Mol Biol, 1985, 182 (2): 295- 315. |
| 14 | FAULKNER R A , DIVERDI J A , YANG Y , et al. The surface of nanoparticle silicon as studied by solid-state NMR[J]. Materials, 2013, 6 (1): 18- 46. |
| 15 | HOFFMANN H C , DEBOWSKI M , MULLER P , et al. Solid-state NMR spectroscopy of metal-organic framework compounds (MOFs)[J]. Materials, 2012, 5 (12): 2537- 2572. |
| 16 | LINDON J C , NICHOLSON J K , HOLMES E , et al. Metabonomics: Metabolic processes studied by NMR spectroscopy of biofluids[J]. Concept Magnetic Res, 2000, 12 (5): 289- 320. |
| 17 | KENYON W E . Nuclear-magnetic-resonance as a petrophysical measurement[J]. Nucl Geophys, 1992, 6 (2): 153- 171. |
| 18 | WISHART D S . Metabolomics: applications to food science and nutrition research[J]. Trends Food Sci Tech, 2008, 19 (9): 482- 493. |
| 19 | JIANG Y , DAVID B , TU P , et al. Recent analytical approaches in quality control of traditional Chinese medicines-A review[J]. Anal Chim Acta, 2010, 657 (1): 9- 18. |
| 20 | BECKER E D . A brief-history of nuclear-magnetic-resonance[J]. Anal Chem, 1993, 65 (6): A295- A302. |
| 21 | LAUTERBUR P C . Image formation by induced local interactions: examples employing nuclear magnetic resonance[J]. Nature, 1973, 242 (5394): 190- 191. |
| 22 | MANSFIELD P , GRANNELL P K . NMR diffraction in solids[J]. J Phys C Solid State, 1973, 6 (22): L422- L426. |
| 23 | SONG Y Q . Low field magnetic resonance: multi-dimensional experiments of relaxation and diffusion[J]. Chinese J Magn Reson, 2015, 32 (2): 141- 149. |
| 23 | 宋一桥. 低场核磁共振: 弛豫和扩散的多维实验[J]. 波谱学杂志, 2015, 32 (2): 141- 149. |
| 24 | SUN Z , XIAO L Z , LIAO G Z , et al. Design of magnets for in situ NMR detection devices intended for preservation of ancient architectures[J]. Chinese J Magn Reson, 2017, 34 (3): 372- 382. |
| 24 | 孙哲, 肖立志, 廖广志, 等. 用于长城等古建筑探测的NMR探测器的磁体设计[J]. 波谱学杂志, 2017, 34 (3): 372- 382. |
| 25 | ZHANG Z F , XIAO L Z , LIU H X , et al. Simulation of restricted diffusion of water molecules in micropores[J]. Chinese J Magn Reson, 2014, 31 (1): 49- 60. |
| 25 | 张宗富, 肖立志, 刘化新, 等. 水分子在微孔隙介质中的受限扩散模拟[J]. 波谱学杂志, 2014, 31 (1): 49- 60. |
| 26 | HE Y G , FENG J W , ZHANG Z , et al. Development of pulsed dynamic nuclear polarization for enhancing NMR and MRI[J]. Chinese J Magn Reson, 2015, 32 (2): 393- 398. |
| 26 | 贺玉贵, 冯继文, 张志, 等. 脉冲动态核极化增强的NMR和MRI系统研究[J]. 波谱学杂志, 2015, 32 (2): 393- 398. |
| 27 | WANG X C , JIANG W L , HUANG C D , et al. Parahydrogen-induced hyperpolarized nuclear magnetic resonance: from basic principle to applications[J]. Spectroscopy and Spectral Analysis, 2020, 40 (3): 665- 673. |
| 27 | 王忻昌, 江文龙, 黄程达, 等. 仲氢诱导超极化增强核磁共振技术: 从原理到应用[J]. 光谱学与光谱分析, 2020, 40 (3): 665- 673. |
| 28 | ZHAO X C , SUN X P , YUAN Y P , et al. Measuring polarization of hyperpolarized xenon-129 gas with low-field NMR[J]. Chinese J Magn Reson, 2016, 33 (3): 458- 467. |
| 28 | 赵修超, 孙献平, 袁亚平, 等. 超极化气体氙-129的低场NMR测量[J]. 波谱学杂志, 2016, 33 (3): 458- 467. |
| 29 | YANG L , BAO Q J , MAO W P , et al. System performance evaluation of a self-developed NMR spectrometer[J]. Chinese J Magn Reson, 2012, 29 (1): 78- 85. |
| 29 | 杨亮, 鲍庆嘉, 毛文平, 等. 自主研制核磁共振波谱仪的性能评估[J]. 波谱学杂志, 2012, 29 (1): 78- 85. |
| 30 | 俎栋林. 核磁共振成像仪——构造原理和物理设计[M]. 北京: 科学出版社, 2015. |
| 31 | CHEN L , SONG K , WANG Y L . Effects of attenuated salmonella typhimurium infection on fecal metabonome in mice-comparison between WIPM and Bruker 500 MHz NMR spectrometers[J]. Chinese J Magn Reson, 2014, 31 (3): 349- 363. |
| 31 | 陈璐, 宋侃, 王玉兰. 感染减毒鼠伤寒沙门氏菌对小鼠粪样代谢组的影响 & mdash; & mdash; WIPM和Bruker 500 MHz核磁共振波谱仪检测结果的比较[J]. 波谱学杂志, 2014, 31 (3): 349- 363. |
| 32 | QU H Y , WANG L , WANG Y H , et al. Design of the superconducting main magnet based on variable density method in cylindrical MRI scanner[J]. IEEE T Appl Supercon, 2020, 30 (4): 4400805. |
| 33 | ZENG Q B , BIE B L , GUO Q N , et al. Hyperpolarized Xe NMR signal advancement by metal-organic framework entrapment in aqueous solution[J]. P Natl Acad Sci USA, 2020, 117 (30): 17558- 17563. |
| 34 | LI H D , ZHAO X C , WANG Y J , et al. Damaged lung gas exchange function of discharged COVID-19 patients detected by hyperpolarized 129Xe MRI[J]. Sci Adv, 2021, 7 (1): eabc8180. |
| 35 | ZHAO Z C , LI X , LI S H , et al. Structural investigation of interlayer-expanded zeolite by hyperpolarized 129Xe and 1H NMR spectroscopy[J]. Micropor Mesopor Mat, 2019, 288, 109555. |
| 36 | WANG W Y , HU H , XU J , et al. Hydrogenation reaction on Pd-Cu bimetallic catalysts: A parahydrogen-induced polarization study[J]. Chinese J Magn Reson, 2018, 35 (3): 269- 279. |
| 36 | 王伟宇, 胡涵, 徐君, 等. Pd-Cu双金属催化剂上加氢反应的仲氢诱导超极化研究[J]. 波谱学杂志, 2018, 35 (3): 269- 279. |
| 37 | SONG Y H , LIU W Q , YAO Y F . Gaining higher NMR signal enhancement with parahydrogen-induced polarization[J]. Chinese J Magn Reson, 2015, 32 (3): 470- 480. |
| 37 | 宋艳红, 刘文卿, 姚叶锋. 仲氢诱导极化增强的核磁共振实验条件优化[J]. 波谱学杂志, 2015, 32 (3): 470- 480. |
| 38 | ARDENKJAER-LARSEN J H . On the present and future of dissolution-DNP[J]. J Magn Reson, 2016, 264, 3- 12. |
/
| 〈 |
|
〉 |