基于PDMS的NMR中色谱技术的分离性能研究
收稿日期: 2014-07-15
修回日期: 2015-07-20
网络出版日期: 2015-09-05
基金资助
国家自然科学基金资助项目(21105108)
Evaluation of Separation Performance of Polydimethylsiloxane-Matrixed Chromatography by NMR
Received date: 2014-07-15
Revised date: 2015-07-20
Online published: 2015-09-05
Supported by
国家自然科学基金资助项目(21105108)
吴瑞1 , 柏正武1* , 杨盈2 , 黄少华2* . 基于PDMS的NMR中色谱技术的分离性能研究[J]. 波谱学杂志, 2015 , 32(3) : 511 -517 . DOI: 10.11938/cjmr20150312
Polydimethylsiloxane (PDMS) has been used as the virtual “stationary phase” (VSP) for chromatographic NMR. Its separation capability towards halogenated compounds was investigated. Diffusion coefficients of n-pentane, 1-bromopentane and 1,5-dibromopentane contained in a mixture were measured with high-resolution liquid-state diffusion-ordered NMR spectroscopy (DOSY). In the absence of PDMS, these diffusion coefficients were close, and as a result, the three components could not be separated. In contrast, the diffusion coefficients were markedly different from each other in the presence of PDMS, leading to excellent separation. In addition, the effects of sample temperature and solution viscosity on separation performance were also investigated. It was observed that separation performance improved as sample temperature rose; and reduced as solution viscosity increased.
Key words： polydimethylsiloxane; virtual stationary phase; chromatography NMR; DOSY; separation
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