新型拟肽cyclo[-RGD-ψ(triazole)-GD-]波谱学数据与结构确证
收稿日期: 2015-03-27
修回日期: 2016-04-08
网络出版日期: 2016-06-05
基金资助
浙江省科技厅公益性技术应用研究计划资助项目(2015C37007);浙江大学实验技术资助项目(SYB201402).
An NMR Spectroscopy Study on Peptidomimetics Cyclo[-RGD-ψ(triazole)-GD-]
Received date: 2015-03-27
Revised date: 2016-04-08
Online published: 2016-06-05
刘雅琴 , 何玲 , 余明新 . 新型拟肽cyclo[-RGD-ψ(triazole)-GD-]波谱学数据与结构确证[J]. 波谱学杂志, 2016 , 33(2) : 337 -344 . DOI: 10.11938/cjmr20160215
The spectral data of peptidomimetics cyclo[-RGD-ψ(triazole)-GD-] were reported, including UV, FT-IR and NMR (i.e., 1H NMR, 1H-1H COSY, 13C NMR, DEPT, 1H-13C HSQC and 1H-13C HMBC). The NMR signals were assigned. The infrared spectrum was analyzed to derive the types of vibrations of the functional groups in the compound. The molecular structure of peptidomimetics cyclo[-RGD-ψ(triazole)-GD-] was determined.
Key words： peptidomimetics; NMR; assignment; chemical shift; structural elucidation
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