SOME APPLICATION STUDIESON STEREOCHEMISTRY BY NOESY

Chinese Journal of Magnetic Resonance ›› 1998, Vol. 15 ›› Issue (6): 489-494.

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SOME APPLICATION STUDIESON STEREOCHEMISTRY BY NOESY

Cui Yuxin¹, Bao Peng², Pan Xinfu², Steve C. F. Au-Yeung³

1. National Research Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Science, Beijing Medical University, Beijing 100083;
2. Department of Chemistry, Lanzhou University, Lanzhou 730000;
3. Department of Chemistry, The Chinese University of Hong Kong, Shatin, N. T. Hong Kong

Received:1998-08-10 Revised:1998-09-14 Published:1998-12-05 Online:2018-01-17

Abstract

Abstract: The two-dimensional Nuclear Overhauser Effect Spectroscopy (NOESY)technique was successfully applied to investigate the structure and stereochemistry problems of organic compounds.In this paper, the configurations, conformations and stereochemistry of isomeric compounds 1-6, derivatives of cyclopropane 7, 8 were researched by using NOESY.The structures of compounds 5-8 were simulated by computer molecular modelling, their results were the same as NOESY.

Key words: NOESY, Isomer, Stereochemistry

Cui Yuxin, Bao Peng, Pan Xinfu, Steve C. F. Au-Yeung. SOME APPLICATION STUDIESON STEREOCHEMISTRY BY NOESY[J]. Chinese Journal of Magnetic Resonance, 1998, 15(6): 489-494.

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SOME APPLICATION STUDIESON STEREOCHEMISTRY BY NOESY

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