Chinese Journal of Magnetic Resonance ›› 1994, Vol. 11 ›› Issue (3): 287-294.

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STUDY ON THE 1H NMR AND STEREOCHEMISTRY OF SUBSTITUTED TETRAHYDRO-β-CARBOLINES

Zhang Li1, Peng Shiqi2, Yang Xianbin2, Ekkehard Winterfeldt3   

  1. 1. Depart. of Chemistry, Beijing University, Beijing 100871;
    2. College of Phar, Science, Beijing Medical University, Beijing 100083;
    3. Institute fur Org. chem. Uni. Hannover, West-Germany
  • Received:1993-06-04 Published:1994-09-05 Online:2018-01-20

Abstract: In this paper the 1H NMR data of 1,2-disubstituted,1,3-disubstituted and 1,2,3,-trisubstituted tetrahydro-β-carbolines are reported,the relationships be-tween the chemical shifts of 1-H and the configurations of 1-C are discussed, and based on the NOE effects the conformation of compounds (1S, 3S) 3 and (1R, 3S) 3 under the experimental conditions were analysed.

Key words: Tetrahydro-β-carbolines, 1H NMR, Confonnation