Chinese Journal of Magnetic Resonance ›› 1987, Vol. 4 ›› Issue (3): 233-239.

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80 MHz 1H-NMR STUDIES OF 2-(4-SUBSTITUTED PHENYL-2-OXO-3-AMIDO-1-AZETIDINYL)-2-PHENYLACETIC ACIDS

Tong Xiaohe1, Li Zhenghua1, Wang Shumei2, Zhuo Yuhua2, Li Shuqiong2   

  1. 1. College of Pharmacy, West China University of Medical Science, Chengdu;
    2. Chengdu Institue of Organic Chemistry, Academia Sinica
  • Received:1986-11-22 Revised:1987-02-24 Published:1987-09-05 Online:2018-01-22

Abstract: In this paper, the identification of twenty new synthesized title compounds (Monolactam derivatives) by 80 MHz 1H-NMR spectra is reported. The stereo-configuration of monolactam ring was proved with coupling constant.All synthesized compounds were concluded to be cis-monolactam derivatives through the resolution of the spectral data in detail. The effect of solvent and substituted group on chemical shift are discussed.

Key words: Monocyclic β-Lactam