Abstract: The carbon-13 NMR spectra of 1-(4-pyridine acyl)-4-phenyl thioscmicarbazide, 1-(4-pyridine acyl)-4-p-chlorO^-phenylthiosemicarbazide, 1-(4-pyridine acyl)-4-p-bromo-phenylthiosemicarba/ide, 3-(4-pyridinyl)-4-phenyl-1, 2, 4-triazoline-5-thionc, 3-(4-pyridinyl)-p-chloro phenyl-1, 2, 4-triazoline-5-thione, 3-(4-pyridinyl)-p-bromo phenyl-1, 2, 4-triazoline-5-thione and their derivatives were studied in this paper. The chemical shifts of various carbon resonance peaks were assigned by the proton-noise decoupling, Off-resonance, APT-technique, and use of empirical methods. At the same time, the substituent effects of 4-hydrazide in monosubstituted pyridinc were obtained. These parameters are Z₄₂ (Z₄₆) 0.1ppm Z₄₃ (Z₄₅)-3.3ppm and Z₄₄ 3.9ppm (solvent:polysol; reference:TMS).

Key words: The effect of substituent, ¹³C-NMR