Chinese Journal of Magnetic Resonance ›› 1989, Vol. 6 ›› Issue (3): 347-351.

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TWO DIMENSIONAL NMR STUDY OF DIHYDROETOPHINE

Miao Zhenchun, Wei Tongtai, Son Yunjin   

  1. Academy of Military Medical Sciences, Beijing
  • Received:1988-06-03 Revised:1988-11-01 Published:1989-09-05 Online:2018-01-22

Abstract: The 1H and 13C NMR spectra of the analgesic dihydroetophine (1) were studied by 1H-1H COSY-NOESY, 13C-1H COSY and long range 13C-1H COSY techniques. The chemical structure of the analgesic was furthur confirmed. In addition, from 2D NOE experimental result, C-7 configuration has been elucidated as (2). The result was confirmed by X-ray diffraction analysis.

Key words: Dihydroetophine, 1H and 13C NMR, 2D NMR, Configuration