Abstract: Biological membrane is an important part of the cell. The biosynthesis of the protein, catalytic mechanism of the enzyme, energy transmit, material convey, nerve impulse transmission, cell-cell recognition, cell cancerology, immunochemistry, hormonal action, metabolism, vision and resperation are closely related to the functions of biological membrane. To study the relationship between structure, especially dynamic structure, and function of biological membrane will provide important scientific basis for solving these problems. Study of membrane protein and biological membrane by ²H NMR is a very effective means for solving them.
Several problems in dynamic structure of membrane protein, especially bacteriorhodopsin of purple membrane, and biological membrane studied by solid state ²H NMR are discussed in this paper on the basis of the new results obtained by us and other authors. These problems are 1). Selection of the method for the study of dynamic structure of membrane proteins and biological membrane. 2). Dynamic structure of purple membrane protein studied by solid state ²H NMR. 3). The model of dynamic micro-structure of bacteriorhodopsin of purple membrane. 4). A contemporary, microscopic fluid mosaic model of dynamic structure of biological membrane by ²HNMR.