Infrared, ultraviolet, NMR (i.e., 1H NMR, 13C NMR, DEPT-135, COSY, HSQC and HMBC), and mass spectroscopic data of cabazitaxel were collected and interpreted. Differential thermal analysis, X-ray power diffraction and elementary analysis were also used to characterize the compound. All 1H and 13C NMR signals were assigned. Possible fragmentation pathways were discussed based on the information provided by the mass spectra. The infrared spectrum was used to analyze the types of vibration of the functional groups in the compound. The structure of the compound was determined.
HAO Fu
,
LI Zhi-gang
,
YU Da-hai
,
KANG Wang
. Spectroscopic Studies and Structural Elucidation of Cabazitaxel[J]. Chinese Journal of Magnetic Resonance, 2017
, 34(2)
: 191
-199
.
DOI: 10.11938/cjmr20170208
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