Azilsartan is a novel AT-1 angiotensin Ⅱ receptor blocker, which reduces blood pressure mildly without the side effect of cough. The drug is believed to have a large market potential. In this study, the drug was analyzed by ultraviolet spectroscopy (UV), infrared spectroscopy (IR), high resolution mass spectrometry (HRMS) and one-/two-dimensional magnetic resonance spectroscopy (i.e., 1H NMR, 13C NMR, DEPT, 1H-1H COSY, HMQC and HMBC). The spectral data were carefully analyzed, interpreted and used to elucidate the structure of the compound.
WANG Ya-lan
,
WANG Xiao-jing
,
WANG Zhi-wei
. Spectral Analyses and Structural Elucidation of Azilsartan[J]. Chinese Journal of Magnetic Resonance, 2019
, 36(3)
: 350
-358
.
DOI: 10.11938/cjmr20182689
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