Review Articles & Perspectives

Review of a New Molecular Imaging Method——Deuterium Metabolic Spectroscopy and Imaging

  • Yi ZHANG ,
  • Fei-yang LOU ,
  • Ke FANG ,
  • Gao CHEN ,
  • Xiao-tong ZHANG
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  • 1. Department of Neurosurgery at the Second Affiliated Hospital of Zhejiang University School of Medicine, Zhejiang University, Hangzhou 310009, China
    2. Interdisciplinary Institute of Neuroscience and Technology, Zhejiang University, Hangzhou 310020, China
    3. Bruker (Beijing) Scientific Technology Co. Ltd., Beijing 100081, China
    4. College of Electrical Engineering, Zhejiang University, Hangzhou 310027, China

Received date: 2022-04-15

  Online published: 2022-06-13

Abstract

Commonly used molecular imaging methods include positron emission tomography (PET), hydrogen magnetic resonance spectroscopy (1H MRS) and imaging (1H MRSI), chemical exchange saturation transfer (CEST), and hyperpolarized 13C MRSI. As a cutting-edge molecular imaging method, deuterium metabolic spectroscopy (DMS) and imaging (DMI) has been recently developed and it distinguishes different tissues according to their specific glycometabolism. Compared with other molecular imaging methods, this promising technique has apparent advantages such as no radioactivity, good stability, and easy to maneuver. In this article, we review the progress of DMS/DMI and discuss its significance, future development, and potential clinical applications.

Cite this article

Yi ZHANG , Fei-yang LOU , Ke FANG , Gao CHEN , Xiao-tong ZHANG . Review of a New Molecular Imaging Method——Deuterium Metabolic Spectroscopy and Imaging[J]. Chinese Journal of Magnetic Resonance, 2022 , 39(3) : 356 -365 . DOI: 10.11938/cjmr20222999

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