Chinese Journal of Magnetic Resonance >

2024 , Vol. 41 >Issue 1: 87 - 98

DOI: https://doi.org/10.11938/cjmr20233060

Articles

Development and Validation of Zero-field NMR Spectrometer Based on Compact Atomic Magnetometer

  • Fangyue FU ,
  • Qingqian GUO ,
  • Xiaoyu FENG ,
  • Jiayu XU ,
  • Zekun YAO ,
  • Tao HU ,
  • Xiaodong YANG ,
  • Yan CHANG
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  • 1. School of Electronic and Information Engineering, Changchun University of Science and Technology, Changchun 130022, China
    2. Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou 215163, China
    3. Jihua Laboratory, Foshan 528200, China
    4. Jinan Guoke Medical Technology Development Co., Ltd, Jinan 250101, China

Received date: 2023-03-26

  Online published: 2023-06-05

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Abstract

Conventional high-field nuclear magnetic resonance (NMR) spectrometer necessitates advanced superconducting technology, which usually involves a magnet of large volume and high maintenance cost. Moreover, strong magnet often has severe magnetic field inhomogeneity, leading to NMR line broadening. Zero- to ultralow-field (ZULF) NMR emerged as a complementary approach to traditional high-field NMR techniques. In this paper, a portable zero-field NMR spectrometer based on a compact atomic magnetometer was developed, which adopted an integrated control system based on a multi-function data acquisition card (National Instruments PCIe-6353). The spectrometer is of a main magnetic field strength less than 1 nT and enables achieving high-resolution J-spectrum under zero-field environment. Specifically, a series of single pulse excitation experiments for the initial adiabatic state was carried out to calibrate the triaxial magnetic field coils. Then a modified composite pulse sequence was developed to further validate the performance of zero-field NMR spectrometer by single-spin control experiments for the 13C-1H spin system.

Key words： zero-field NMR; J-spectroscopy; atomic magnetometer; single-spin control

Cite this article

Fangyue FU , Qingqian GUO , Xiaoyu FENG , Jiayu XU , Zekun YAO , Tao HU , Xiaodong YANG , Yan CHANG . Development and Validation of Zero-field NMR Spectrometer Based on Compact Atomic Magnetometer[J]. Chinese Journal of Magnetic Resonance, 2024 , 41(1) : 87 -98 . DOI: 10.11938/cjmr20233060

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