Chinese Journal of Magnetic Resonance >
Design of a Portable Magnetic Resonance Multi-source RF Pulse Generator
Received date: 2024-11-11
Online published: 2024-12-20
In the field of magnetic resonance imaging (MRI), multi-source emission can improve the uniformity of radio frequency (RF) magnetic field and the quality of MRI images. In this paper, we propose a portable MRI multi-source RF pulse generator design based on the Zynq 7000 SoC all programmable system-on-chip. The design consists of a host computer software with fully open pulse sequence parameters and a fully digitalized, highly integrated, dual credit card-sized hardware board, which outputs multiple RF pulse signals with independently adjustable waveform, frequency, phase, and amplitude in parallel. The hardware description language Verilog is used to build AXI DDS (advanced eXtensible interface direct digital synthesizer) and multiplier circuits inside the FPGA (field programmable gate array) to realize the functions of generating multiple RF pulse signals and signal modulation. The experimental results show that the design can correctly transmit four MRI RF pulse signals, providing a fully digital, reconfigurable, compact, and feasible solution for developing a portable magnetic resonance multi-source RF pulse generator.
LIU Ying , YUAN Binhua , ZHANG Haowei . Design of a Portable Magnetic Resonance Multi-source RF Pulse Generator[J]. Chinese Journal of Magnetic Resonance, 2025 , 42(3) : 285 -298 . DOI: 10.11938/cjmr20243137
| [1] | 俎栋林. 核磁共振成像仪——构造原理和物理设计[M]. 北京: 科学出版社, 2015. |
| [2] | Bernstein M. Handbook of MRI pulse sequences[M]. Massachusetts: Elsevier, 2004. |
| [3] | 周帅. 基于FPGA与直接数字合成的磁共振射频发生研究[D]. 北京: 北京化工大学, 2021. |
| [4] | 徐勤. 数字化磁共振成像谱仪[D]. 上海: 华东师范大学, 2006. |
| [5] | LI Y W, XIAO L. Magnetic resonance imaging RF pulse generator based on FPGA and DDS[J]. Chinese J Magn Reson, 2016, 33(4): 590-596. |
| 李聿为, 肖亮. 基于FPGA与DDS的磁共振成像射频脉冲发生器[J]. 波谱学杂志, 2016, 33(4): 590-596. | |
| [6] | ZHU Y F, HE W, HE C H, et al. Nuclear magnetic resonance RF pulse generator based on digital modulation technique[J]. Chinese J Magn Reson, 2018, 35(3): 318-327. |
| 朱云峰, 何为, 何传红, 等. 基于数字调制技术的核磁共振射频脉冲发生器[J]. 波谱学杂志, 2018, 35(3): 318-327. | |
| [7] | LU S, CHANG Y, QIAN S S, et al. Optimized design of selective RF pulses for simultaneous multilayer MRI[J]. Chinese J Magn Reson, 2018, 35(2): 141-149. |
| 卢杉, 常严, 钱嵩松, 等. 用于同时多层MRI的选择性射频脉冲的优化设计[J]. 波谱学杂志, 2018, 35(2): 141-149. | |
| [8] | XIAO L, WANG W. A radio-frequency source using direct digital synthesis and field programmable gate array for nuclear magnetic resonance[J]. Rev Sci Instrum, 2009, 80: 124703. |
| [9] | JIANG Y, JIANG Y, TAO H, et al. A complete digital radio-frequency source for nuclear magnetic resonance spectroscopy[J]. Rev Sci Instrum, 2002, 73: 3329-3331. |
| [10] | SON H W, CHO Y K, GOPINATH A, et al. B1+ shimming with SAR reduction in high-field MRI[J]. J Electromagn Waves Appl, 2013, 27(12): 1521-1524. |
| [11] | AFLAKI P, MOHAMMADI A, NEGRA R, et al. A new approach to design a frequency synthesizer using direct digital synthesis technique[C]// Canadian Conference on Electrical and Computer Engineering, Niagara Falls, ON, Canada: IEEE, 2008: 001733-001736. |
| [12] | DE MENEZES N R, HERNANDEZ H D, CARVALHO D, et al. All-digital FPGA-based RF pulsed transmitter with hardware complexity reduction techniques[C]// Symposium on Integrated Circuits and Systems Design (SBCCI), Campinas, Brazil: IEEE, 2020: 1-5. |
| [13] | KUOY E, GLAVIS-BLOOM J, HOVIS G, et al. Point-of-care brain MRI: preliminary results from a single-center retrospective study[J]. Radiology, 2022, 305(3): 666-671. |
| [14] | LIU Y, LEONG A T, ZHAO Y, et al. A low-cost and shielding-free ultra-low-field brain MRI scanner[J]. Nat Commun, 2021, 12(1): 7238. |
| [15] | MAZUREK M H, CAHN B A, YUEN M M, et al. Portable, bedside, low-field magnetic resonance imaging for evaluation of intracerebral hemorrhage[J]. Nat Commun, 2021, 12(1): 5119. |
| [16] | KIMBERLY W T, SORBY-ADAMS A J, WEBB A G, et al. Brain imaging with portable low-field MRI[J]. Nat Rev Bioeng, 2023, 1(9): 617-630. |
| [17] | JIANG M, LU S B, LI Y, et al. Compact multi-channel radio frequency pulse-sequence generator with fast-switching capability for cold-atom interferometers[J]. Rev Sci Instrum, 2023, 94(9): 093204. |
| [18] | 刘朝阳, 张志, 毛文平. 一种多通道核磁共振射频信号发射机: 中国, 201210209555.8[P]. 2014-08-13. |
| [19] | HAN H, EIGENTLER T W, WANG S, et al. Design, implementation, evaluation and application of a 32-channel radio frequency signal generator for thermal magnetic resonance based anti-cancer treatment[J]. Cancers, 2020, 12(7): 1720. |
| [20] | USMANI M N. FPGA controlled RF pulse generator for teaching MRI[D]. Texas: Texas A&M University, 2021. |
| [21] | HE G, WANG W M. A multi-source RF transmitter for high-field MRI[J]. Chinese J Magn Reson, 2017, 34(3): 338-346. |
| 何刚, 王为民. 一种用于高场MRI的多源射频发射机[J]. 波谱学杂志, 2017, 34(3): 338-346. |
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