Chinese Journal of Magnetic Resonance >
Development of Pulsed Dynamic Nuclear Polarization for Enhancing NMR and MRI
Received date: 2014-03-10
Revised date: 2015-05-08
Online published: 2015-06-05
Supported by
Grant from the special equipment of scientific instrument of Chinese Academy of Sciences, the Ministry of Science and Technology of China (2011YQ120035) and the National Natural Science Foundation of China (11405264).
In this report, we present a pulsed dynamic nuclear polarization (DNP) system, being reconfigurable for DNP enhanced magnetic resonance imaging (DNP-MRI) and magnetic resonance spectroscopy (DNP-MRS). Several novel console designs are proposed in the presented DNP system. A distributed digital architecture based on Peripheral Component Interconnect Express (PCIe) has been developed, so as to significantly improve the efficiency of data transmission and communication reliability as well as the precise control of pulse sequence. An external high speed Double Data Rate (DDR) memory chip is used for storing FID data and pulse sequence elements, greatly speeding up the execution of the pulse sequence and reducing the interval of TR and improving the accuracy of TR in image sequence. Using clock phase-shift technology, we can produce digital pulse accurately with high timing resolution of nanosecond timescales. Finally, two experimental examples for DNP-MRS and DNP-MRI are shown.
Key words： NMR; MRI; pulsed DNP; console; PCIe
HE Yu-gui1 , 2 , FENG Ji-wen1* , ZHANG Zhi1 , 3 , WANG Chao1 , 3 , NI Sheng1 , HU Shao-bin1 , WANG Dong1 , CHEN Fang1 , LIU Mai-li1 , LIU Chao-yang1* . Development of Pulsed Dynamic Nuclear Polarization for Enhancing NMR and MRI[J]. Chinese Journal of Magnetic Resonance, 2015 , 32(2) : 393 -398 . DOI: 10.11938/cjmr20150221
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