Chinese Journal of Magnetic Resonance >
Spectral Analysis and Structural Elucidation of Tenofovir Disoproxil Fumarate
Received date: 2014-10-11
Revised date: 2015-07-21
Online published: 2015-09-05
Supported by
沈阳药科大学大学生创新创业训练计划资助项目
Ultraviolet spectrum, infrared spectrum, mass spectra and nuclear magnetic resonance spectra (i.e., 1H NMR, 13C NMR, 31P NMR, DEPT-135, COSY, HSQC and HMBC) of tenofovir disoproxil fumarate were collected and interpreted. All NMR signals were assigned. Based on the mass spectral data, the possible fragmentation pathways were discussed. The infrared spectrum was used to analyze the types of vibration of the functional groups in the compound. The structure of the compound was determined.
SONG Ai-hua1 , ZHANG Yan-feng2 , SHA Yi1 , GAO Yuan3 , LI Ning3 , MA Yue-ping3* . Spectral Analysis and Structural Elucidation of Tenofovir Disoproxil Fumarate[J]. Chinese Journal of Magnetic Resonance, 2015 , 32(3) : 542 -550 . DOI: 10.11938/cjmr20150315
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