Chinese Journal of Magnetic Resonance >
Gaining Higher NMR Signal Enhancement with Parahydrogen-Induced Polarization
Received date: 2014-10-31
Revised date: 2015-07-22
Online published: 2015-09-05
Supported by
国家自然科学基金资助项目(21174039)
Parahydrogen-induced polarization (PHIP) can enhance NMR signals significantly, and thus has shown great prospects in chemistry, biology, medical science and so on. In practice, the amplitude of NMR signal enhancement by PHIP, however, is often limited by experiment setup. In this work, it was demonstrated the signal enhancement in PHIP experiments can be optimized by choosing appropriate experimental conditions, including temperature, pressure and the way to introduce parahydrogen into the PHIP experiment. The reaction system of 1-hexyne and [Rh(COD)(dppb)]BF4 was chosen as the example to illustrate how to optimize experimental conditions in PHIP experiments.
SONG Yan-hong , LIU Wen-qing , YAO Ye-feng* . Gaining Higher NMR Signal Enhancement with Parahydrogen-Induced Polarization[J]. Chinese Journal of Magnetic Resonance, 2015 , 32(3) : 470 -480 . DOI: 10.11938/cjmr20150308
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