定量NMR中多种检出限评估方法的比较

陈雷,刘红兵,刘惠丽

Comparison of Different Approaches for Estimation of the Detection Limit of Quantitative NMR

Lei CHEN,Hong-bing LIU,Hui-li LIU

表3 不同采样次数下，信噪比回归曲线法中的拟合参数及计算出的检出限

Table 3 Fitting parameters and limits of detection calculated by the signal-to-noise ratio regression method with different numbers of scan

16 32 48 64 96 128 ${a_{SN}}$ 34.0846 50.1219 58.5726 63.4292 70.8545 89.1259 ${b_{SN}}$ 1.0401 1.5872 2.0016 2.3365 2.9585 3.3478 R2 0.9949 0.9953 0.9956 0.9961 0.9963 0.9964 ${S_{y/x - SN}}$ 5.6671 8.2389 10.1284 11.1132 13.5773 15.2679 XD/(μmol/L) 16.3 15.6 15.2 14.3 13.8 13.7