LC-DAD-SPE-NMR/MS技术用于卡巴他赛注射液中微量未知杂质的鉴定
Identification and Structural Characterization of an Unknown Trace Degradation Impurity in Cabazitaxel Injection by LC-DAD-SPE-NMR/MS
LC-DAD-SPE-NMR/MS技术用于卡巴他赛注射液中微量未知杂质的鉴定 |
| 刘红兵, 刘惠丽, 罗立廷, 孙丽娟, 陈雷 |
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Identification and Structural Characterization of an Unknown Trace Degradation Impurity in Cabazitaxel Injection by LC-DAD-SPE-NMR/MS |
| LIU Hongbing, LIU Huili, LUO Liting, SUN Lijuan, CHEN Lei |
| 图4 (a)卡巴他赛与(b)降解杂质萃取物1H NMR谱（600 MHz，氘代乙腈，298 K）. *：氘代乙腈溶剂残余峰 |
| Fig. 4 1H NMR spectra of (a) cabazitaxel and (b) trapped analyte (600 MHz, in CD3CN, 298 K). * : residual peak of CD3CN |
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