致痫剂量尼古丁对青少年雌性大鼠海马结构的影响

陈茜, 刘思婕, 蔡悦, 程琳琳, 王旭霞, 康彦, 林富春, 雷皓

Effects of Seizure-inducing Doses Nicotine on Hippocampal Structure in Adolescent Female Rats

CHEN Xi, LIU Sijie, CAI Yue, CHENG Linlin, WANG Xuxia, KANG Yan, LIN Fuchun, LEI Hao

图4 尼古丁对青少年雌性大鼠背侧海马亚区短期内组织学/免疫组织学的影响，*代表p < 0.05. (a) GM增大区域以及HE、GFAP、IBA1染色的背侧海马冠状面展示，正方形方框代表亚区的位置；(b)背侧海马亚区的HE、GFAP染色代表图；(c)背侧海马亚区IBA1染色代表图以及IOD与小胶质细胞胞体面积的统计结果

Fig. 4 Short-term nicotine effects on histology / immunohistology of dorsal hippocampal subregions in adolescent female rats, * : p < 0.05. (a) Dorsal hippocampal coronal sections of the GM enlarged regions and HE, GFAP, and IBA1staining, with square boxes indicating the locations of subregions; (b) representative images of HE and GFAP staining in subregions of the dorsal hippocampus; (c) representative images of IBA1 staining in subregions of the dorsal hippocampus, along with statistical results of IOD and microglial soma area