19F NMR化学位移编码的cRGD靶向双模态探针多色成像
19F NMR Chemical Shift-encoded cRGD-targeted Dual-modal Probe for Multicolor Imaging
19F NMR化学位移编码的cRGD靶向双模态探针多色成像 |
| 李娜, 肖龙, 李莎, 刘昱墩, 贾宇舒, 张磊, 陈世桢 |
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19F NMR Chemical Shift-encoded cRGD-targeted Dual-modal Probe for Multicolor Imaging |
| LI Na, XIAO Long, LI Sha, LIU Yudun, JIA Yushu, ZHANG Lei, CHEN Shizhen |
| 图5 活体荧光成像与定量分析. (a) A549荷瘤小鼠经尾静脉注射Cy-F-cRGD（100 μmol/L，100 μL）或Cy-F-PEG（100 μmol/L，100 μL）后，在2、4、6、8、12和24 h进行体内荧光成像（λex = 710 nm，λem = 760 nm），红色虚线圈为肿瘤区域；(b)肿瘤区域内荧光强度的定量分析结果 |
| Fig. 5 In vivo fluorescence imaging and quantitative analysis. (a) In vivo fluorescence images of A549 tumor-bearing mice at 2, 4, 6, 8, 12, and 24 h after intravenous injection of Cy-F-cRGD (100 μmol/L, 100 μL) or Cy-F-PEG (100 μmol/L, 100 μL) (λex = 710 nm, λem = 760 nm). Red dashed circles indicate tumor regions; (b) Quantitative analysis of fluorescence intensity in the tumor regions |
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