Chinese Journal of Magnetic Resonance ›› 1983, Vol. 1 ›› Issue (1): 123-126.
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Gao Xiaoju1, Liu Shuxun2
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Abstract: Garamine is an aminoglycoside with biological activity Its PKa values where determined over the PH range 2-13 by C-13NMR method. Data obtained in the experiment were analyzed by nonlinear regression method.Three PKa values have been obtained:PK1=5.45. PK2=6.75, PK3=8.70. The present information can provide a basis for further study of metabolism of aminoglyco -sides in livnig body.
Gao Xiaoju, Liu Shuxun. DETERMINATION OF GARAMINE PKa BY CARBON-13 NUCLEAR MAGNETIC RESONANCE[J]. Chinese Journal of Magnetic Resonance, 1983, 1(1): 123-126.
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