Abstract: The unique carbon skeleton of 2(5H)-furanone is widely present in a variety of bioactive natural products, optically active γ-substituted butenolides are also useful as chiral synthons for synthesis of a lot of biologically active natural products. It is significant to study the NMR properities of these kinds of compounds because there has been a considerable interest in the synthesis and properities of γ-substituted butenolides recently. In this paper the ¹H NMR and ¹³C NMR of a series of compounds of optically pure 5-((-)-bornyloxy)-3,4-disubstituted-2(5H)-furanone has been made. The effect of substituent groups on structure and chemical shift has been studied also.

Key words: ¹H NMR, ¹³C NMR, Optically pure γ-butenolides