ESR STUDIES ON ABILITIES OF SELENIUM CONTAINING ABZYMES SCAVENGED OH·

Chinese Journal of Magnetic Resonance ›› 2000, Vol. 17 ›› Issue (5): 401-406.

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ESR STUDIES ON ABILITIES OF SELENIUM CONTAINING ABZYMES SCAVENGED OH·

DONG Feng-xia¹, ZHENG Ying-guang¹, QI Dan-hua², LUO Gui-min², YANG Tong-shu³

1. Analysis And Test Center, Jilin University, Changchun 130023;
2. Key Lab of Molecular Enzymology and Enginering of Educational Ministry, Jilin University, Changchun 130023;
3. Institute of Endemic Diseases, Bethune M edical University, Changchun 130021

Received:2000-06-28 Revised:2000-08-16 Published:2000-10-05 Online:2018-01-11

Abstract

Abstract: m1c8 and m4G3 are selenium-contaning abzymes with glutathione peroxidase activity and the two abzymes could scavenge free radicals.Their abilities to scavenge OH· were examined in iron containing Xanthine oxidase/hypoxathine system by using spin trapping method. It was found that the abilities of these two Se-abzymes to scavenge OH· did surpass the level of native glutathione peroxidase. m1c8 was the best one.

Key words: Se-abzyme, HO·radical, ESR, Spin-trapping

CLC Number:

O482.53⁺3

DONG Feng-xia, ZHENG Ying-guang, QI Dan-hua, LUO Gui-min, YANG Tong-shu. ESR STUDIES ON ABILITIES OF SELENIUM CONTAINING ABZYMES SCAVENGED OH·[J]. Chinese Journal of Magnetic Resonance, 2000, 17(5): 401-406.

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ESR STUDIES ON ABILITIES OF SELENIUM CONTAINING ABZYMES SCAVENGED OH·

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