Chinese Journal of Magnetic Resonance ›› 2001, Vol. 18 ›› Issue (4): 305-314.

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STRUCTURAL STUDY OF PIPERAZINYLETHYLESTRONE ETHER

HAN Hai, ZHANG Qiang, LI Zhang-wan,  WENG Ling-ling, ZHENG Hu   

  1. Department of Pharmacy, Sichuan University, Chengdu 610041
  • Received:2001-06-30 Revised:2001-09-04 Published:2001-12-05 Online:2001-12-05
  • About author:*Correspondence author
  • Supported by:

    国家自然科学基金重点资助项目.

Abstract:

Piperazinylethylestrone ether is a new synthesized compound that can be used for  the prevention and treatment of osteoporosis and other disease caused by osteop orosis. For further study on it, in this article, the structure of piperazinylet hylestrone ether was established by using a series of spectral techniques (e.g . IR, MS, NMR) especially two-dimensional 1H-1H COSY, HMQC and HMBC which can provide valuable information. This combination of these techniques is applicable f or the ass ignment of highly overlapping signals and makes it possible to completely assign  the 1H-1H and 13C NMR spectra signals of piperazinylethylestrone e ther.

Key words: Piperazinylethylestrone ether, Structure, Analyze, 2D NMR

CLC Number: