STRUCTURE ELUCIDATION OF ELISABATIN B WITH QUATERNARY CARBONS BY 2D NMR SPECTROSCOPY

Chinese Journal of Magnetic Resonance

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STRUCTURE ELUCIDATION OF ELISABATIN B WITH QUATERNARY CARBONS BY 2D NMR SPECTROSCOPY

SHI Yan-ping¹, WU Qin-juan¹, RODRIGUEZ Abimael D²

1.Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, China；
2.Department of Chemistry, University of Puerto Rico, P.O.Box 23346, Río Piedras, Puerto Rico 00931-3346, USA

Received:2002-03-11 Revised:2002-04-04 Published:2002-12-05 Online:2002-12-05
Supported by:
中国科学院“百人计划”基金资助项目（2000年）.

Abstract

Abstract:

2D NMR (¹H-¹H COSY, HMQC and HMBC) methods, among which the HMBC metho d was the most important, were used to elucidate the structure of Elisabatin B ( i.e, diterpene with 11 quaternary carbons). The ¹H and ¹³C chemi cal shifts were assigned. Compared with the results reported in reference, the chemical sh if ts of 11 more quaternary carbons were determined. The results of this study sugg est that the 2D NMR techniques can be applied to and are useful in structural el ucidation of natural products.

Key words: 2D NMR, Spectroscopic analysis, Elisabatin B

CLC Number:

O482.53

SHI Yan-ping1, WU Qin-juan1, RODRIGUEZ Abimael D2. STRUCTURE ELUCIDATION OF ELISABATIN B WITH QUATERNARY CARBONS BY 2D NMR SPECTROSCOPY[J]. Chinese Journal of Magnetic Resonance.

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STRUCTURE ELUCIDATION OF ELISABATIN B WITH QUATERNARY CARBONS BY 2D NMR SPECTROSCOPY

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