Chinese Journal of Magnetic Resonance ›› 2006, Vol. 23 ›› Issue (2): 247-251.

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Assignment of 13C and 1H Chemical Shifts of Potassium Sodium  Dehydroandrographolide Succinate

  

  1. Center of Instrumental Analysis, Shenyang Pharmaceutical University, Shenyang 110016, China
  • Received:2005-05-16 Revised:2005-11-21 Published:2006-06-05 Online:2006-06-05

Abstract:

Potassium sodium dehydroandrographolide succinate (PSDS) is a new antibacterial and antiviral agent derived from andrographolide, a compound found in the extract of medicinal herb Andrographis paniculata (Burm. f.) Nees. In this study, the 13C and 1H chemical shifts of the compound were assigned using 1D NMR and 2D NMR techniques including gCOSY, gHSQC, gHSQC-TOCOSY and gHMBC. Its structure was determined from the NMR data.

Key words: 2D NMR, chemical shift assignments, potassium sodium dehydroandrographolide succinate, andrographolide

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