Chinese Journal of Magnetic Resonance >
Association of 129Xe Ventilation Functional MRI with Pulmonary Lesion Types
Received date: 2024-03-23
Online published: 2024-04-09
This study investigates the correlation between 129Xe ventilation functional MRI and CT-detected pulmonary lesion types. We performed 129Xe ventilation functional MRI and CT scans on a sample of 143 patients, subsequently analyzing the relationship between lung ventilation function at the lobe level and CT lesion types. The findings suggest that the ventilation function from 129Xe MRI was consistent with CT results in the majority of lung lobes (74.6%). The ventilation function impairment of lung correlates with CT lesion types, particularly in instances of mixed diseases and emphysema/bullae, which are more prone to induce lung ventilation dysfunction. Moreover, distinct ventilation patterns are observed among different lesion types. That is, the data from both 129Xe ventilation functional MRI and CT provide complementary insights. The preliminary finding of this study offers data support for evaluating lung ventilation function caused by lung lesions, and provides more references for clinical imaging diagnosis, thereby contributing to the refinement of diagnostic and therapeutic strategies for pulmonary diseases.
CHEN Qi , LI Haidong , FANG Yuan , SHEN Luyang , LIU Wuji , LUO Ming , LI Yecheng , ZHANG Ming , ZHAO Xiuchao , SHI Lei , ZHOU Qian , HAN Yeqing , ZHOU Xin . Association of 129Xe Ventilation Functional MRI with Pulmonary Lesion Types[J]. Chinese Journal of Magnetic Resonance, 2024 , 41(3) : 276 -285 . DOI: 10.11938/cjmr20243103
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