NMR STUDIES OF AMPELOPTIN SEPARATED FROM AMPELOPSIS MEGALOPHYLLA DIELS ET GILG

Chinese Journal of Magnetic Resonance ›› 1998, Vol. 15 ›› Issue (5): 395-402.

NMR STUDIES OF AMPELOPTIN SEPARATED FROM AMPELOPSIS MEGALOPHYLLA DIELS ET GILG

Zhang Hanping¹, Yan Jiangli², Mao Xi'an², Shen Lianfang²

1. Pharmaceutical School, Medical University of Tongji, Wuhan 430030;
2. State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, Wuhan Institute of Physics and Mathematics, The Chinese Academy of Sciences, Wuhan 430071

Received:1998-07-10 Revised:1998-07-30 Published:1998-10-05 Online:2018-01-17

Abstract

Abstract: An effective component was separated from traditional Chinese medicine ampelopsis megalophylla diels et gilg and studied by 2D ¹H-¹³C heteronuclear multibond coherence spectroscopy (HMBC), ¹H-¹³C heteronuclear multiquantum coherence spectroscopy (HMQC)and proton exchange spectroscopy (EXSY).It is suggested that the compound is ampeloptin (3, 3', 4', 5, 5', 7-hexa-hydoxy dihydroflavonol), which is first obtained from ampelopsis megalophylla diels et gilg.Chemical shifts of proton and ¹³C were assigned more accurately.Protonation of solvent DMSO was also investigated and discussed in detail.

Key words: Ampelopsis megalophylla diels et gilg, Ampeloptin, Chemical shift, HM BC, Solvent protonation

Zhang Hanping, Yan Jiangli, Mao Xi'an, Shen Lianfang. NMR STUDIES OF AMPELOPTIN SEPARATED FROM AMPELOPSIS MEGALOPHYLLA DIELS ET GILG[J]. Chinese Journal of Magnetic Resonance, 1998, 15(5): 395-402.

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NMR STUDIES OF AMPELOPTIN SEPARATED FROM AMPELOPSIS MEGALOPHYLLA DIELS ET GILG

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