Chinese Journal of Magnetic Resonance ›› 2006, Vol. 23 ›› Issue (3): 361-365.

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1H NMR Characteristics of New Carboplatin Derivatives

LIU Wei-ping, GAO Chuan-zhu, CHEN Xi-zhu, QIU Ming-hua   

  1. 1.State Key Laboratory Phytochemistry and Plant Resource in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, China; 2.Kunming Institute of Precious Metals, Kunming 650221, China
  • Received:2005-12-13 Revised:2006-02-07 Published:2006-09-05 Online:2009-12-05
  • Contact: QIU Ming-hua

Abstract:

Carboplatin is one of the most important anticancer drugs among the second generation of platinum metal-based drugs, and widely used in clinics. To find new carbopaltin drugs with stronger anticancer efficacy, six new carbopaltin derivatives were synthesized. In the paper, the 1H NMR chemical shift assignment of 4 new carbopaltin derivatives was obtained, and the 1H NMR characteristics of these compounds was also discussed.

Key words: 1H NMR, assignments, carboplatin, anticancer drugs

CLC Number: