The Structure of a Furanosesquiterpenoid Extracted from Myrrh Elucidated by NMR Spectroscopy

Chinese Journal of Magnetic Resonance ›› 2008, Vol. 25 ›› Issue (4): 541-548.

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The Structure of a Furanosesquiterpenoid Extracted from Myrrh Elucidated by NMR Spectroscopy

YANG Guo-chun¹; LI Zhan-lin¹; LI Wen²; HUA Hui-ming¹*

(1.School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China; 2.School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China)

Received:2008-05-04 Revised:2008-06-24 Published:2008-12-05 Online:2009-12-05
Contact: Hua Hui-ming

Abstract

Abstract: A furanosesquiterpenoid, 2-methoxy-5-acetoxy-furanogermacr-1(10)E-en-6- one was isolated from the CHCl₃ extrct of myrrh. Its structure was established by its 1D and 2D NMR (i.e, ¹H-¹H COSY, HSQC and HMBC) spectra. The ¹H and ¹³C chemical shifts of the compound were assigned. The relative stereochemistry of the 1, 10-double bond and that of the methoxyl, methyl, and acetoxy groups were determined by NOESY experiments and analyses of the coupling constants.

Key words: NMR, chemical shift assignment, 2D NMR, myrrh, furanosesquiterpenoid, relative stereochemistry

CLC Number:

O641

YANG Guo-chun¹; LI Zhan-lin¹; LI Wen²; HUA Hui-ming¹*. The Structure of a Furanosesquiterpenoid Extracted from Myrrh Elucidated by NMR Spectroscopy[J]. Chinese Journal of Magnetic Resonance, 2008, 25(4): 541-548.

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The Structure of a Furanosesquiterpenoid Extracted from Myrrh Elucidated by NMR Spectroscopy

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