Chinese Journal of Magnetic Resonance

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STRUCTURE ELUCIDATION FOR SOME DRUGS USING NMR TECHNIQUES

JIANH Gao-xi,LI Qin,LIU Xue-hui,CIU Yu-xin*   

  1. National Research Laboratory of Natural and Biomimetic Drugs, Medical and Healthy Analysis Center, Peking University, Beijing 100083, China;
    Team Academy of Pharmaceutical Science, Beijing 100071, China
  • Received:2003-06-02 Revised:2003-07-06 Published:2003-12-05 Online:2003-12-05
  • About author:*Correspondence author: Cui Yu-xin,E-mail:yxcui@bjmu.edu.cn,Tel:(010)82802377.

Abstract:

The structures of several drugs, namely Lorartadine, Etodolac, Formoterol Fumarate and Zaleplon, were elucidated by 1D NMR and 2D NMR techniques (gCOSY, gNOESY, gHSQC, gNMBC). The 1H and 13C NMR chemical shifts of these compounds were assigned.

Key words: NMR, Lorartadine, Etodolac, Formoterol, Zaleplon

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