Chinese Journal of Magnetic Resonance ›› 2006, Vol. 23 ›› Issue (3): 313-319.

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Spectroscopic Data Derived Structure of Lafutidine

ZHAO Ru-sheng, YANG Ri-fang, YUN Liu-hong, LIU He   

  1. Institute of Pharmacology and Toxicology, Academy of Military Medical Sciences, Beijing 100850,China
  • Received:2005-11-13 Revised:2005-12-23 Published:2006-09-05 Online:2009-12-05
  • Contact: YANG Ri-fang

Abstract: Mass spectrum and one-dimensional (1H and 13C ) and two-dimensional (heteronuclear multiple-bond coherence, HMBC) NMR spectra of lafutidine were reported and interpreted. The 1H and 13C chemical shifts were assigned. The spectroscopic characteristics of the compound were discussed in detail and found to be consistent with its structure known previously.

Key words: NMR, mass spectrometry, chemical shift assignment, lafutidine

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