Chinese Journal of Magnetic Resonance

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LC-UV-NMR-MS: INFORMATION-RICH SEPARATIONS

Iain Green   

  1. Varian, Inc., 3120 Hansen Way, Palo Alto, CA 94303, U.S.A.
  • Received:2003-11-10 Published:2003-12-05 Online:2003-12-05
  • About author:iaig.green@varianinc.com.He received his Ph.D.from the niversity of London (London,U.K.)in Physical Organic Chemistry and has since held a variety of positions in the analytical industry. Joining the NMR Marketing Group at Varian Inc. in 1998.

Abstract:

The availability of liquid chromatography-ultraviolet-nuclear magnetic resonance-mass spectrometry (LC-UV-NMR-MS)integrated systems is providing greater information content and confidence for a variety of sample types, such asdrug metabolites, natural products, impurities, and degradants. A wide range of experimental strategies can be pur-sued, highlighting the flexibility and performance possible with this multihyphenated technique.

Key words: LC-UV-NMR-MS, NMR, metabolites, natural products, IFC, Chili-Probe

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