Chinese Journal of Magnetic Resonance ›› 2006, Vol. 23 ›› Issue (4): 467-472.

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Structure Elucidation of A New Immunosuppressant FTY720 by NMR

CHENG Cai-fa1*; JIANG Hong1; LIU Xin-you3; ZHANG Xue-mei2; 
FENG You-jian1; TU Shu-jiang1,2
  

  1. (1.The Key Laboratory of Biotechnology for Medicinal Plants of Jiangsu Province, Xuzhou 221116, China; 2.Department of Chemistry, Xuzhou Normal University, Xuzhou 221116, China; 3.Department of Pharmacy of Tangdu Hospital, The Fourth Military Medical University, Xi′an 710038, China)
  • Received:2006-03-15 Revised:2006-05-15 Published:2006-12-05 Online:2009-12-05
  • Contact: CHENG Cai-fa

Abstract: NMR (1H NMR, 13C NMR, DEPT, HSQC, HMBC) methods were used to elucidate the structure of a new immunosuppressant FTY720 (2-amino-[2-(4-octylphenyl) ethy1]-1, 3 propanediol hydrochloride). The 1H and 13C chemical shifts of the compound were assigned.

Key words: NMR, immunosuppressant, FTY720, chemical shift, spectroscopic analysis

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