NMR Studies of Two Furostanol Saponins Isolated from Polygonatum Kingianum

Abstract

Abstract:

A pair of stereoisomeric furostanol saponins were isolated from fresh rhizomes of Polygonatum kingianum, and identified as 26-O-β-D-glucopyranosyl 25(S)-furostane-5-en-3β, 22, 26-triol-12-on-3-O-β-D-glucopyranosyl (1→4)-β-D-fucopyranoside (1) and 26-O-β-D-glucopyranosyl 25(R)-furostane-5-en-3β, 22, 26-triol-12-on-3-O-β-D-glucopyranosyl (1→4)-β-D- fucopyranoside (2), respectively, by 1D ¹H and ¹³C NMR and 2D NMR (including ¹H-¹H COSY, HSQC and HMBC). ¹H and ¹³C chemical shifts of the two compounds were completely assigned, and the configurations of the methyl group at C-25 were determined.

Key words: NMR, furostanol saponin, Polygonatum kingianum

CLC Number:

O641

ZHANG Jie, MA Bai-Ping, KANG Li-Ping, YU He-Shui, YANG Yun, YA Xian-Zhong. NMR Studies of Two Furostanol Saponins Isolated from Polygonatum Kingianum[J]. Chinese Journal of Magnetic Resonance, 2006, 23(1): 31-40.

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