Chinese Journal of Magnetic Resonance ›› 2010, Vol. 27 ›› Issue (1): 126-131.

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Determination of Spin-Lattice Relaxation Time of Water under High Magnetic Field

  

  1. Beijing National Laboratory for Molecular Sciences (BNLMS), Center for Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China
  • Received:2009-12-15 Published:2010-03-05 Online:2010-03-05

Abstract:

The inversion-recovery pulse sequence used for routine measurement of spinlattice relaxation time (T1) was modified to measure T1 of water under high magnetic field (14.1 T). A pair of bipolar pulsed field gradients were added to suppress the effects of radiation damping, which often occurs with concentrated sample such as water. With this method, the relaxivity of commercial magnetic resonance imaging (MRI) contrast agent Gd-DTPA in aqueous solution was measured and found to be similar to the value reported in the literature. The method was also used to evaluate the performance of a newlysynthesized MRI contrast agent compound TEMDP-EMFs.

Key words: NMR, spin-lattice relaxation time, inversion recovery, radiation damping

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