A Simple Method for Clean Water Signal Suppression

A Simple Method for Clean Water Signal Suppression

MAO Xi-an*

State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, Wuhan Center for Magnetic Resonance (Wuhan Institute of Physics and Mathematics, Chinese Academy of Sciences), Wuhan 430071, China

Received:2013-10-08 Revised:2013-11-07 Published:2014-03-05 Online:2014-03-05
About author:*Corresponding author：MAO Xi-an, Tel: +01-216-368-7068, E-mail: xian.mao@case.edu.

HSQC experiments are the most basic experiments in protein NMR. In HSQC experiments, water suppression is mainly achieved by a pair of field gradient pulses whose intensity ratio is in accordance with the ratio of the heteronuclear gyromagnetic ratios. In this paper, a simple method is propsed to achieve clean water suppression in HSQC experiments by properly modulating the gradient pulse length.

CLC Number:

O482.53

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MAO Xi-an. A Simple Method for Clean Water Signal Suppression[J]. Chinese Journal of Magnetic Resonance.

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References

[1] Zhang X, Mao X A, Liu M L. Solvent Resonance Suppression Methods in NMR Spectroscopy//Encyclopedia of Spectroscopy & Spectrometry[M]. in press.

[2] Zheng G, Price W S. Solvent signal suppression in NMR[J]. Prog NMR Spectr, 2010, 56: 267－288.

[3] Hurd R E, John B K. Gradient-enhanced proton-detected heteronuclear multiple-quantum coherence spectroscopy[J]. J Magn Reson, 1990, 91: 648－653.

[4] Vuister G W, Boelens R, Kaptein R, et al. Gradient-Enhanced HMQC and HSQC spectroscopy. Applications to ¹⁵N labeled Mnt repressor[J]. J Am Chem Soc, 1991, 113: 9 688－ 9 690.

[5] Chen Jin-hong(陈金鸿), Mao Xi-an(毛希安). Radiation damping effects in NMR experiments of pulsed field gradients(脉冲梯度场实验中的辐射阻尼效应)[J]. Chinese J Magn Reson(波谱学杂志), 1996, 13(6): 547－555.

[6] Piotto M, Saudek V, Sklenar V. Gradient-tailored excitation for single-quantum NMR spectroscopy of aqueous solutions[J]. J Biomol NMR, 1992, 2: 661－665.

[7] Liu M L, Mao X A, Ye C H, et al. Improved WATERGATE pulse sequences for solvent suppression in NMR spectroscopy[J]. J Magn Reson, 1998, 132: 125－129.

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