Diagnostic Efficacy Comparison of B-scan Ultrasonography and MRI in Fetal Skeletal Abnormalities

doi:10.11938/cjmr20253143

Abstract

Abstract:

Magnetic resonance imaging (MRI) demonstrates significant value in the diagnosis of fetal skeletal abnormalities during the second trimester. Current clinical practice confronts challenges in improving diagnostic accuracy and assessing the impact of diagnosis on pregnancy outcomes, while conventional prenatal B-scan ultrasonography has limitations in diagnostic efficacy. From January 2021 to January 2024, this study analyzed the second-trimester imaging reports of 58 cases who were confirmed with fetal skeletal abnormalities after labor induction or delivery, revealing MRI's superior diagnostic performance compared to B-scan ultrasonography in the detection rate of fetal skeletal abnormalities, the diagnostic coincidence rate of induced abortion recommendations and overall excellent image quality rate. The diagnostic value of MRI for detecting fetal skeletal abnormalities in the second trimester makes it a reliable technique to provide fetal skeletal information for pregnant women and their families, which is conducive to pregnancy outcomes and healthy birth, and has broad clinical application prospects.

Key words: magnetic resonance imaging, second trimester fetus, skeletal malformations, pregnancy outcome, diagnostic value

CLC Number:

O482.53

SHU Wei. Diagnostic Efficacy Comparison of B-scan Ultrasonography and MRI in Fetal Skeletal Abnormalities[J]. Chinese Journal of Magnetic Resonance, 2025, 42(3): 265-274.

Figures/Tables 10

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References 21

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检查方式	AUC	灵敏度	特异性	约登指数	标准误	P值	95%CI
B超检查	0.792	81.65%	77.83%	0.595	0.12	<0.001	0.705~0.808
MRI检查	0.902	90.17%	88.53%	0.787	0.15	<0.001	0.839~0.943
联合检查	0.925	90.39%	89.04%	0.794	0.10	<0.001	0.894~0.944

检查方式	优	良	差	优良
B超检查	48（82.76）	2（3.45）	8（13.79）	50（86.21）
MRI检查	52（89.66）	4（6.89）	2（3.45）	56（96.55）
χ²				3.940
P				0.047

骨骼畸形种类	实际发生例数	B超检出例数	MRI检出例数
足内翻	13（22.41）	10（17.24）	13（22.41）
多（并）指、趾	9（15.52）	7（12.07）	9（15.52）
手缺失	9（15.52）	8（13.79）	9（15.52）
桡骨缺失	6（10.34）	5（8.62）	6（10.34）
颅骨缺失	5（8.62）	5（8.62）	5（8.62）
股骨不等长	3（5.19）	2（3.45）	2（3.45）
尾端退化综合征	2（3.45）	1（1.73）	1（1.72）
脊柱裂	7（12.06）	5（8.62）	6（10.34）
骨不全	4（6.89）	3（5.17）	4（6.89）
总计	58（100.00）	46（79.31）	55（94.84）