Chinese Journal of Magnetic Resonance ›› 2006, Vol. 23 ›› Issue (2): 253-259.

• Articles • Previous Articles     Next Articles

An NMR Study of New Drug Cefpirome Sulfate

  

  1. Center of Instrumental Analysis, Shenyang Pharmaceutical University, Shenyang 110016, China
  • Received:2005-10-17 Revised:2006-01-16 Published:2006-06-05 Online:2006-06-05

Abstract:

The structure of cefpirome sulfate, a new compound belonging to the fourth generation super broad-spectrum cephalosporins antibiotics, was studied using 1D  and 2D  NMR techniques. Complete assignments of the 1H, 13C  and 15N NMR chemical shifts were obtained. The structural parameters obtained from the NOESY experiment were found to be useful for determining its stereo-structure.

Key words: NMR, cefpirome sulfate, chemical shift assignment

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